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Microarrays Help Map Transcription Factors of Disease on a Genomic Scale 2/26/04

February 26, 2004 11:03 am | Articles | Comments

by Elizabeth Tolchin Chromatin immunoprecipitation combined with promoter microarrays helped a group of researchers map the location of three transcription factors in the pancreas and liver to identify the genes they regulate.

New Products for siRNA Gene Silencing Released 2/25/04

February 25, 2004 5:46 am | Articles | Comments

by Elizabeth Tolchin Two new products for small, interfering RNA (siRNA) targeting are promising reliable gene silencing for researchers in functional genomics or drug target identification, according to the companies who released the products.

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Ex Taq Polymerase For Real-Time PCR

February 24, 2004 8:38 am | Articles | Comments

Real-time PCR offers a quantitative method for viral and bacterial pathogen detection, measurement of gene expression, and mutation detection.

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Whole Genome Amplification Kit

February 24, 2004 8:38 am | Articles | Comments

GenomePlex™ whole genome amplification (WGA) point of use kit (Rubicon Genomics, Inc.) complements Rubicon's WGA in-house service business that was launched earlier this year.

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GPCR Clones

February 24, 2004 8:38 am | Articles | Comments

OriGene Technologies Inc. has announced the addition of the GPCR CloneSet™, a designated subset of over 300 full-length human non-olfactory G protein-coupled receptors, to the TrueClone™ Collection product line.

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Microarray Labeling

February 24, 2004 8:38 am | Articles | Comments

Label IT®μ Array Biotin Kits (Mirus Corp.) offer a single color, chemical labeling method optimized for use in microarray applications.

Yeast Shuttle Vector

February 24, 2004 8:38 am | Articles | Comments

Yeast shuttle vector pORF-CLONE provides cost-effective selection of clones containing long cDNA inserts with a correct open reading frame (ORF).

Gene Silencing In Difficult To Transfect Cells

February 24, 2004 8:38 am | Articles | Comments

Ambion's pSilencer ™ adeno 1.0-CMV System combines the advantages of adenoviral vectors with an efficient siRNA expression system. It allows easy delivery of an siRNA expressing construct into many difficult to transfect cells, including primary cells.

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Broad pH Range IPG Strips

February 24, 2004 8:38 am | Articles | Comments

Immobiline DryStrip™ gels extend the pH range in the basic region from 10 to 11, compared to the traditional pH 3-10, yielding a broad overview of protein composition, enhancing gel resolution, and improving reproducibility of the protein pattern in the extreme basic region.

DNA Polymerase Mix

February 24, 2004 8:38 am | Articles | Comments

BD Qtaq™ DNA Polymerase Mix is a full-length Taq DNA polymerase optimized for use with BD Qzyme™ Assays and most other qPCR detection applications and provides increased DNA and RNA quantitation sensitivity and reproducibility in qPCR and RT-PCR.

Supercoiled DNA Marker Set

February 24, 2004 8:38 am | Articles | Comments

Supercoiled DNA Marker Set is suitable for size analysis of cDNA clones and BAC subclones by agarose minigel or Pulse-Field Gel Electrophoresis (e.g., FIGE, CHEF). It can also be used for the size analysis of any supercoiled plasmid larger than 8 kb and other extra-chromosomal DNAs from any source.

IEF Fractionation System (2811)

February 24, 2004 8:38 am | Articles | Comments

Solution phase isoelectric focusing with the ZOOM™ IEF Fractionator provides reproducible

Transcription Structure Captured 2/23/04

February 23, 2004 11:52 am | Articles | Comments

by Elizabeth Tolchin A picture of the inner structure of RNA polymerase is providing a better picture of the transcription process. The structure, transcription factor IIB (TFIIB) bound to RNA polymerase II (pol II), was solved by a group at Stanford University, Stanford Calif.

MicroRNAs Could Become Cancer Targets 2/20/04

February 20, 2004 11:05 am | Articles | Comments

by Elizabeth Tolchin MicroRNAs are frequently located in cancer-associated regions of the genome and can act as both tumor suppressor genes and oncogenes, according to a new study. The association could lead to the use of microRNAs in cancer treatment.

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Canadian Company Goes Back to the Well 2/19/04

February 19, 2004 12:14 pm | Articles | Comments

by Elizabeth Tolchin An assay technology for screening and select compounds that regulate immune responses developed by the University of British Columbia, Vancouver, Canada, was licensed recently to the Canadian company GeneMax Pharmaceuticals Inc., also in Vancouver.

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