Intrinsic and acquired drug resistance to various classes of chemically diverse chemotherapy agents (referred to as "MultiDrug Resistance", MDR) represents the major obstacle in modern cancer chemotherapy.
by Robert Ford An assay technology developed by a Hungarian company should enable researchers at MDS Pharma Services, Montreal, Canada, to better ensure that patients using multiple medications are receiving the full dosage of their medication rather than excreting them.
by Elizabeth Tolchin With antiquated legislation going back to the Wild West days, Arizona is one of the only remaining states to not allow its universities to take equity positions in companies stemming from scientific discoveries by faculty. That may change in November when a new bill concerning technology transfer will be posted with the state general election.
by Elizabeth Tolchin As part of a phase I Small Business Innovation Research (SBIR) grant from the National Cancer Institute, Bethesda, Md., Aastrom Biosciences Inc. will conduct a $124,000, eight-month study to demonstrate the feasibility and advantages of their technology to culture T lymphocytes or T cells for treatment against malignant melanoma.
by Elizabeth Tolchin Inserting a 2´-O-methyl oligonucleotide into a cell can inhibit small RNA function. That was the method demonstrated by researchers from the University of Massachusetts Medical School, Worcester.
by Elizabeth Tolchin Researchers at the University of Illinois, Chicago, are developing an interactive gene expression map of the brain, as part of The Human Brain Project (HBP).
by Elizabeth Tolchin A baculovirus-based method permits insect cells infected with a virus encoding a library of peptides to display unique major histocompatibility complexes (MHCs) on their surface.
by Elizabeth Tolchin A pioneer in developing procedures for creating mouse models for gene targeting has now developed a technique for altering the level of expression of a chosen gene in mice without changing its function.
by Robert Ford A five-year agreement between Mississippi State University (MSU), Starkville, Miss., and Toxin Alert Inc., Toronto, Canada, plans to provide research funding to the university for the development of large-scale antibody production in tobacco plants.
Model DV990 Microplate Reader is available with or without UV reading capability. In the visible part of the spectra it covers 400-800 nm range. The unit can be equipped with 4-6 filters. Single, double and trichromatic wavelength measurements can be performed.
PhoenIX Ion Exchange Plasmid Purification System utilizes a solid-phase column with patented resin to both optimize purification and enhance the degree of separation between different biomolecules.
The Life Science and Drug Discovery Research Product Guide features optimized 96-well filter plates for membrane-based bioassays and bioseparations.
Full-color, 272-page Furniture Catalog presents a complete line of metal and wood casework, countertops, fixtures, sinks, tables, seating, fume hoods, workstations, appliances, pre-fabricated rooms, shelving, carts, safety items, and accessories for new and renovated laboratory facilities.
Mirus Corp. 2003/2004 catalog provides product data and technical information on nucleic acid delivery and labeling reagents. Discover Trans IT® Transfection Reagents are optimized for specific cell lines and applications such as plasmid and siRNA delivery.
Peptide aggregates are associated with several diseases, including Alzheimer's and Huntington's Disease. Surface plasmon resonance (SPR) -amyloid peptide (Ab) (1-40) was monitored