by Don Monroe, PhD The US Food and Drug Administration reported in January what it called a rebound in approval of innovative drugs in 2003.
Phospho-ERK1/ERK2 DuoSet® IC ELISA Development System kits (R&D Systems) provide an alternative to Western blots for intracellular factors involved in signal transduction, apoptosis, and transcription.
Anti-human TCR V?12.1 monoclonal antibody is for validated applications including flow cytometry, immunoprecipitation, frozen tissue staining, and T cell activation. Anti-human TCR V?6.
Miltenyi Biotec has announced the release of several new MACS® products for the isolation of untouched human B cells.
The Z'-LYTE assay platform (Invitrogen Corp.) provides a fluorescence-based biochemical
Diagnostic Systems Laboratories, Inc. has launched an Inhibin B ELISA. It is specific for dimeric Inhibin B, does not require sample pretreatment, and can be fully automated on open-platform microplate systems.
Pefakit® TAFI is a highly specific, 2-step chromogenic assay for the measurement of TAFI (Thrombin Activatable Fibrinolysis Inhibitor) in plasma.
HSP27 [pS82] phosphoELISA is sensitive to 1,000 cells/well, demonstrated with HeLa cell lysates. Additional validated cell lines include THP-1, HT1080, Jurkat and 293 cells.
HDAC8 Colorimetric/Fluorometric Activity Assay/Drug Discovery Kit is HTS-friendly assay and allows real-time monitoring of HDAC activity. This is made possible by HDAC-TRAC substrate and buffer, which also enables a choice of either colorimetric or fluorometric detection.
BioFX's chemiluminescent substrates are used in immunoassay and immunoblotting applications. The reagents are intensified and the signal duration increased by proprietary enhancers.
ProteomeLab IgG purity/heterogeneity assay (Beckman Coulter) is offered in kit format with a validated standard operating protocol (SOP).
STEAP (Six-transmembrane epithelial antigen of the prostate) is a prostate-specific cell surface antigen that is highly expressed in human prostate cancers. STEAP is unique among cell surface prostate antigens in its potential function as a channel or transport protein.
Technoclone monoclonal antibodies, proteins, plasma proteins, ELISAs and other products for research on vascular diseases include products for the study of coagulation, thrombophilia, thrombosis and lipid metabolism research.
Murine Monoclonal Antibody recognizes 8-hydroxy-deoxyguanosine, 8-hydroxy-guanine and 8-hydroxy-guanosine. The antibody can be used in ELISA and immunohistochemistry to detect these markers of oxidative damage to DNA and RNA.
New series of ELISAs and Instant ELISA kits is offered for the detection of soluble co-stimulatory molecules. The products are useful for research into how manipulation of of the co-stimulatory signals enhance or terminate immune responses.