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Finding the Lessons in VIOXX 9/30/04

September 30, 2004 12:48 pm | Articles | Comments

By Elizabeth Tolchin

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FRET And FRET-FLIM Microscopy Imaging Of Localized Protein Interactions In Living Cell Nucleus

September 30, 2004 9:44 am | Articles | Comments

FRET microscopy imaging is widely used to detect protein-protein interactions inside living cells. This application note describes the use of one and two-photon FRET and in characterizing the dimerization of C/EBP?

Attaching Substrates to DNA Bares Unknown Reactions 9/29/04

September 29, 2004 11:13 am | Articles | Comments

By Elizabeth Tolchin

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One Pharma's Trash Is Another's Pharmacogenomic Treasure 9/28/04

September 28, 2004 8:11 am | Articles | Comments

By Elizabeth Tolchin

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Bulky Molecules Seek Out SNPs 9/27/04

September 27, 2004 9:18 am | Articles | Comments

By Elizabeth Tolchin

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Weekly News Roundup 9/24/04

September 24, 2004 11:39 am | Articles | Comments

By Elizabeth Tolchin

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Quantitative Diagnostics from Yale Forms Basis of New Company 9/23/04

September 23, 2004 10:20 am | Articles | Comments

By Elizabeth Tolchin

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Linear RNA Amplification For Expression Analysis

September 23, 2004 6:42 am | Articles | Comments

RNA amplification is rapidly becoming a routine and necessary step when preparing samples for expression analysis— particularly when using microarrays. RNA amplification provides the sensitivity to detect expression differences of low abundance transcripts that is critical to obtaining a complete understanding of the biology of a given system.

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Tube Shows Minimal Affinity For Peptides And Proteins

September 23, 2004 6:42 am | Articles | Comments

Sample preparation in biological and biotechnological systems plays an important role in the success of many processes. It is a requirement that the material of the micro test tubes used must possess low affinity for proteins and peptides to prevent adsorption of the sample material to the tube surface.

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Shotgun Microarraying a Favorite for Disease Studies 9/22/04

September 22, 2004 12:02 pm | Articles | Comments

By Elizabeth Tolchin

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Algorithm Quickly Exposes Regulatory Elements 9/21/04

September 21, 2004 12:50 pm | Articles | Comments

By Elizabeth Tolchin

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Automated Cell-Based Screening

September 21, 2004 10:49 am | Articles | Comments

A plate handler has been integrated with the Opera high throughput confocal screening system, permitting fully automated cell-based screening.

16-Bit CCD Camera

September 21, 2004 10:49 am | Articles | Comments

The Cascade:128 CCD camera can collect more than 500 full frames of true 16-bit date per second. Faster frame rates can be achieved via subregion readout or binning.

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Digital Confocal Microscope

September 21, 2004 10:49 am | Articles | Comments

The Digital Eclipse C1-Plus Modular Confocal System (Nikon Instruments) features scan head optics that boost optical performance to 400 nm.

4Pi Fluorescence Microscope

September 21, 2004 10:49 am | Articles | Comments

The Leica TCS 4Pi fluorescence microscope system use a phase and wavefront corrected, double-objective imaging system linked to a confocal scanner to enable a 4 to 7-fold increase in axial resolution over confocal and two-photon microscopy.

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