Demethylation therapy suggested
A U.S. Food and Drug Administration (FDA) advisory committee voted 7-2 to recommend the approval of Pfizer’s, New York, Exubera, the long-anticipated inhaled insulin product for treatment of Type 1 and Type 2 diabetes.
Listing of drug developments and approvals
MF75 filter units and bottle top filters incorporate the sterilization-grade Supor machV membrane from Pall Corp. The membranes are composed of polyethersulfone (PES), the same material used for processing biological and pharmaceutical samples for drug discovery and basic research.
Protein solubility is a critical factor for successful 2-D gel electrophoresis; a good result requires that the proteins to be separated be well solubilized prior to and throughout the separation procedure. Protein solubilization is the process of breaking interactions involved in protein aggregation
Yeast cell diagram to model gene/protein interactions
Micromax refrigerated and ventilated microcentrifuge is suited for use in a number of settings, including DNA/RNA molecular biology, clinical and forensic labs. The unit can produce force up to 21,000 × g at speeds of 15,000 rpm. It accelerates to full speed in <15 sec, minimizing wait time.
DeCyder MS Differential Analysis Software enables bench scientists to complete liquid chromatography-mass spectrometry (LC-MS) based differential protein expression analysis without the need for mass-tag chemistry. Researchers can visualize differences and trends in LC-MS/MS data.
Infotrieve/ELN 2.4 electronic laboratory notebook (ELN) enterprise software package allows experimental data to be securely collected, analyzed, stored and shared.
The GPCR SARfari is a comprehensive and easily accessible knowledge-base covering a group of receptors exploited in drug discovery. The tool covers many of the most important G protein-coupled receptors (GPCRs).
NanoDrop ND-3300 fluorospectrometer performs full spectrum fluorescent analysis of one microliter samples without the use of cuvettes or capillaries. The instrument’s sample retention system uses surface tension to hold the sample in place on a fiber optic measurement surface.
Bioscreen microbiology growth curve analysis system runs up to 200 growth curves at a time automatically. The user loads a honeycomb plate cuvette, sets experimental conditions and walks away. The system measures turbidity in growth media, plotting it kinetically over time.
Non-lytic insect-based protein expression system Triple Express combines an expression cassette
Incorporating proprietary E. cloni technology, EXPRESS BL21(DE3) competent cells provide efficient cloning and protein expression. With a transformation efficiency of > 5 × 10 9 cfu/μg, E.
This line of chromatography sorbents is available for protein separation and purification for biotechnology drug discovery, development and production. The media integrate with a portfolio of membranes, protein purification technologies and services.